Specific Autoantibody Signature Was Seen In Subset Of People With MS Long Before Clinical Symptoms Appeared, Researchers Find

MedPage Today (4/19, George) reported, “A specific autoantibody signature was seen in a subset of people with multiple sclerosis (MS) long before clinical symptoms appeared, blood samples showed.” Investigators found that “a distinct set of autoantibodies emerged in approximately 10% of MS patients up to 5 years before symptoms were seen.” These “autoantibodies appeared to bind to both human cells and common pathogens and were associated with higher levels of serum neurofilament light.” The findings were published in Nature Medicine.