Patients With Immunosuppression At Increased Risk For Poor Outcomes With Neuroinvasive West Nile Virus, Study Finds

Infectious Disease Advisor (5/21, Nye) reports, “Patients with immunosuppression are at increased risk for poor outcomes and severe clinical manifestations when infected with neuroinvasive West Nile virus, according to study results published in JAMA Network Open.” In the study, “analysis between the groups showed that patients with immunosuppression required longer hospital stays (median, 16 [IQR, 11-26] vs 8 [5-20] days) and experienced significantly higher rates of crude 90-day mortality (28% vs 7%). After adjustment for disease severity, the significant difference in mortality between groups persisted (adjusted hazard ratio [HR], 2.22; 95% CI, 1.07-4.27; P =.03).”