Mutation In IGFBP7 Gene Linked To Reversal In Disease Progression, Partial Or Full Recovery In People With ALS, Study Finds

ALS News Today (8/6, Wexler) reports, “A mutation in the IGFBP7 gene is associated with a very rare phenomenon in which people with amyotrophic lateral sclerosis (ALS) have a reversal in disease progression and experience partial or full recovery, a new study reports.” Because the mutation leads to “less production of the resulting protein IGFBP7, the findings suggest that inhibiting that protein may have therapeutic benefits for” patients with ALS. The findings were published in Neurology.