Patients With T2D Recently Diagnosed With Diabetic Retinopathy Have Reduced Concentration Of Progranulin In Tears Compared With Control Patients, Study Finds

Healio (11/13, Mahoney) reports, “Patients with type 2 diabetes recently diagnosed with diabetic retinopathy had a significantly reduced concentration of progranulin in their tears compared with control patients, according to prospective study results.” Considering the correlation investigators “found between progranulin (PGRN) levels and corneal subbasal nerve changes, PGRN may serve as a biomarker for noninvasively diagnosing and predicting the progression of diabetic neurotrophic keratopathy, the researchers wrote in the study.” The findings were published in Translational Vision Science & Technology.