LN Diagnosis Could Improve If Early Results With Multimarker Urine Test Are Confirmed In Larger Studies, Research Suggests

MedPage Today (11/18, Gever) reports “lupus nephritis (LN) diagnosis could improve greatly if early results with a multimarker urine test are confirmed in larger studies, research” suggested. The study found that “measurement of 12 biomarkers in urine, yielding a numerical score for LN activity, led to an area under the receiver operating characteristic curve (AUC) of 0.90, whereas presence of proteinuria – the usual means for detecting LN – had an AUC of just 0.61, not much better than random chance.” The findings were presented at ACR Convergence 2024.