Immune Responses To RSV Vaccines Tended To Fall Short In Older People With Weakened Immunity, Study Finds

January 02, 2025

MedPage Today (12/31, Lou) reported, “Immune responses to respiratory syncytial virus (RSV) vaccines tended to fall short in older people with weakened immunity, a study found.” Investigators found that “in 38 immunocompromised persons who received either the RSVPreF3-AS01E (RSVA-AS01E; Arexvy) or RSVpreF (Abrysvo) vaccine, preF IgG antibody titers rose a median 4.21-fold by 4 weeks – with 61% of the group meeting seroconversion, or criteria for immune response to RSV vaccination.” The findings were published in a research letter in JAMA.